Director/PDMR Shareholding

GlaxoSmithKline PLC
30 March 2007



   Notification of Transactions of Directors, Persons Discharging Managerial
                      Responsibility or Connected Persons



I give below details of changes in the interests of Directors, Persons
Discharging Managerial Responsibility or Connected Persons in the Ordinary
Shares and Ordinary Share ADRs ("ADRs") of GlaxoSmithKline plc ("the Company").


   26 March 2007     Abacus (GSK) Trustees Limited, as trustee of the
                     GlaxoSmithKline Employee Trust, ("the GSK Trust"), sold 
                     2,839 Ordinary Shares in the Company at a price of £13.99 
                     per share on behalf of participants in the GlaxoSmithKline 
                     Share Value Plan.


                     The GSK Trust transferred 15,482 Ordinary Shares of
                     GlaxoSmithKline plc to participants in the GlaxoSmithKline
                     Share Value Plan.


   28 March 2007     The GSK Trust transferred 17,505 Ordinary Shares in the 
                     Company to participants in the SmithKline Beecham Employee 
                     Share Option Plan 1991.


The Company was advised of these transactions on 29 March 2007.

The GSK Trust is a discretionary trust of which all employees or former
employees of GlaxoSmithKline plc and its subsidiaries are potential
beneficiaries. Three of the Company's directors, Dr JP Garnier, Dr M M Slaoui
and Mr J S Heslop are therefore interested in the shares held in the GSK Trust
from time to time in the same way as other employees or former employees of
GlaxoSmithKline plc and its subsidiaries.

This notification relates to a transaction notified in accordance with
Disclosure Rule 3.1.4R(1)(b).


S M Bicknell
Company Secretary


30 March 2007



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