Director/PDMR Shareholding

GlaxoSmithKline PLC
10 April 2006


   Notification of Transactions of Directors, Persons Discharging Managerial
                      Responsibility or Connected Persons


I give below details of an increase in interests in the Ordinary Shares of
GlaxoSmithKline plc in respect of the personal holdings of the under-mentioned
persons at a price of £14.89 per Ordinary Share, following the re-investment of
the dividend paid to shareholders on 6 April 2006.

Mr R Bondy                                                 259
Mr J Heslop                                                162
Mrs C Pulman                                               15
Dr D Pulman                                                80
Mr A Witty                                                 1
Mrs C Witty                                                305


The Company and the above named persons were advised of this information on 7
April 2006.

This notification relates to a transaction notified in accordance with
Disclosure Rules 3.1.4R(1)(a) and 3.1.4R(1)(b).


S M Bicknell
Company Secretary

10 April 2006


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