Director/PDMR Shareholding

GlaxoSmithKline PLC
10 April 2006


   Notification of Transactions of Directors, Persons Discharging Managerial
                      Responsibility or Connected Persons


The Administrators of the GlaxoSmithKline Executive Supplemental Savings Plan
notified the Company and the under-mentioned persons on 7 April 2006 of changes
in their interests in Ordinary Share ADRs arising from an increase in their
interests under the Annual Investment Plan feature following the re-investment
of the dividend paid to shareholders on 6 April 2006 at a price of $51.87 per
share:-


Dr F Calhoun                                                    376.350

Dr J P Garnier                                                  365.125

Mr D Stout                                                      299.566

Dr T Yamada                                                     234.938


This notification relates to a transaction notified in accordance with
Disclosure Rules 3.1.4R(1)(a) and 3.1.4R(1)(b).



S M Bicknell
Company Secretary


10 April 2006



                      This information is provided by RNS
            The company news service from the London Stock Exchange