Director/PDMR Shareholding

GlaxoSmithKline PLC
04 April 2007






   Notification of Transactions of Directors, Persons Discharging Managerial
                      Responsibility or Connected Persons



I give below details of changes in the interests of Directors, Persons
Discharging Managerial Responsibility or Connected Persons in the Ordinary
Shares of GlaxoSmithKline plc.


   26 March 2007           The Administrators of the SmithKline Beecham Employee Benefit Trust ("the
                           Trust") notified the Company on 3 April 2007 that 2,427 Ordinary shares had
                           been sold on 26 March 2007 on behalf of a participant in the SmithKline
                           Beecham Annual Investment Plan at a price of £13.99 per share.



                           The Trust notified the Company on 3 April 2007 that 3,405 Ordinary shares had
                           been transferred on 26 March 2007 to a participant in the SmithKline Beecham
                           Annual Investment Plan.











   27 March 2007           The Trust notified the Company on 3 April 2007 that 1,175 Ordinary shares had
                           been sold on 27 March 2007 on behalf of participants in the SmithKline Beecham
                           Bonus Investment Plan at a price of £13.75 per share



                           The Trust notified the Company on 3 April 2007 that 2,534 Ordinary shares had
                           been transferred on 27 March 2007 to participants in the SmithKline Beecham
                           Bonus Investment Plan.






   29 March 2007           The Trust notified the Company on 3 April 2007 that 1,884 Ordinary shares has
                           been sold on 29 March 2007 on behalf of a participant in the SmithKline
                           Beecham Annual Investment Plan at a price of £13.80 per share.



                           The Trust notified the Company on 3 April 2007 that 2,688  Ordinary shares had
                           been transferred on 29 March 2007 to a participant in the SmithKline Beecham
                           Annual Investment Plan.



The Trust is a discretionary fund of which all non US employees or former
employees of GlaxoSmithKline plc and its subsidiaries are potential
beneficiaries. One of the Company's directors, Mr J S Heslop is therefore
interested in the shares held in the fund from time to time in the same way as
other non US employees or former employees of GlaxoSmithKline plc and its
subsidiaries.



This notification relates to a transaction notified in accordance with
Disclosure Rule 3.1.4R(1)(b).





S M Bicknell

Company Secretary



4 April 2007


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