Director/PDMR Shareholding

GlaxoSmithKline PLC
12 January 2007


   Notification of Transactions of Directors, Persons Discharging Managerial
                      Responsibility or Connected Persons

The Administrators of the SmithKline Beecham Mid-Term Incentive Plan notified
the Company and the under-mentioned persons on 12 January 2007 of an increase in
their interests in Ordinary Share ADRs at a price of $54.67 per ADR following
the re-investment of the dividend paid to shareholders on 4 January 2007.

Dr JP Garnier                                                      1,431.16
Dr F Calhoun                                                       146.28
Mr D Phelan                                                        276.03
Mr D Stout                                                         110.33

This notification relates to a transaction notified in accordance with
Disclosure Rules 3.1.4R(1)(a) and 3.1.4R(1)(b).

S M Bicknell
Company Secretary

12 January 2007


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