Director/PDMR Shareholding

GlaxoSmithKline PLC
17 January 2007




   Notification of Transactions of Directors, Persons Discharging Managerial
                      Responsibility or Connected Persons


I give below details of changes in the interests of Directors, Persons
Discharging Managerial Responsibility or Connected Persons in the Ordinary
Shares of GlaxoSmithKline plc.


   16 January 2007      Abacus (GSK) Trustees Limited, as trustee of the
                        GlaxoSmithKline Employee Trust, ("the GSK Trust"), 
                        transferred 15,312 Ordinary Shares in the Company to 
                        participants in the SmithKline Beecham Employee Share 
                        Option Plan 1991.


   16 January 2007      The GSK Trust transferred 219,000 Ordinary Shares in 
                        the Company to participants in the GlaxoSmithKline 
                        Share Value Plan.


The Company was advised of these transactions on 17 January 2007.

The GSK Trust is a discretionary trust of which all employees or former
employees of GlaxoSmithKline plc and its subsidiaries are potential
beneficiaries. Three of the Company's directors, Dr J-P Garnier, Dr M M Slaoui
and Mr J S Heslop are therefore interested in the shares held in the GSK Trust
from time to time in the same way as other employees or former employees of
GlaxoSmithKline plc and its subsidiaries.

This notification relates to a transaction notified in accordance with
Disclosure Rule 3.1.4R(1)(b).



S M Bicknell
Company Secretary


17 January 2007





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