Director/PDMR Shareholding

GlaxoSmithKline PLC
09 January 2006




   Notification of Transactions of Directors, Persons Discharging Managerial
                      Responsibility or Connected Persons


The Administrators of the GlaxoSmithKline Executive Supplemental Savings Plan
notified the Company and the under-mentioned persons on 9 January 2006 of
changes in their interests in Ordinary Share ADRs arising from an increase in
their interests under the Annual Investment Plan feature following the
re-investment of the dividend paid to shareholders on 5 January 2006 at a price
of $51.95 per share:-


Mr W Calhoun                                                    271.944

Dr J P Garnier                                                  263.833

Mr D Stout                                                      216.461

Dr T Yamada                                                     169.762

Mr J Ziegler                                                    69.733



This notification relates to a transaction notified in accordance with
Disclosure Rules 3.1.4R(1)(a) and 3.1.4R(1)(b).





S M Bicknell
Company Secretary



9 January 2006


                      This information is provided by RNS
            The company news service from the London Stock Exchange