Director/PDMR Shareholding

GlaxoSmithKline PLC
10 January 2006




   Notification of Transactions of Directors, Persons Discharging Managerial
                      Responsibility or Connected Persons





I give below details of changes in interests in the Ordinary Share ADRs of
GlaxoSmithKline plc in respect of the under-mentioned person arising from the
reinvestment of the dividend paid to Ordinary Share ADR holders on 5 January
2006 through the US Global BuyDirect Plan administered by The Bank of New York:



Mrs P Phelan acquired a beneficial interest in 0.2108 Ordinary Share ADRs
purchased at a price of $52.4640 per ADR.





The Company and the above named person were advised of this information on 10
January 2006.



This notification relates to a transaction notified in accordance with
Disclosure Rule 3.1.4R(1)(a).





S M Bicknell

Company Secretary



10 January 2006


                      This information is provided by RNS
            The company news service from the London Stock Exchange