Director/PDMR Shareholding

GlaxoSmithKline PLC
11 January 2006


   Notification of Transactions of Directors, Persons Discharging Managerial
                      Responsibility or Connected Persons

The Administrators of the GlaxoSmithKline Performance Share Plan notified the
Company and the under-mentioned persons on 10 January 2006 of an increase in
their interests in Ordinary Share ADRs at a price of $52.29 per ADR following
the re-investment of the dividend paid to shareholders on 5 January 2006.

Dr W Calhoun                                               35.579

Dr J P Garnier                                             249.127

Mr D Phelan                                                53.383

This notification relates to a transaction notified in accordance with
Disclosure Rules 3.1.4R(1)(a) and 3.1.4R(1)(b).

S M Bicknell
Company Secretary

11 January 2006


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