Director/PDMR Shareholding

GlaxoSmithKline PLC
24 April 2007


   Notification of Transactions of Directors, Persons Discharging Managerial
                      Responsibility or Connected Persons


Following a re-valuation of the cash element of the notional investment held
within the US Retirement Savings Plan ("The Plan"), which is notionally held in
GSK Ordinary Share ADRs, the Administrators of the Plan notified GlaxoSmithKline
plc and the under-mentioned persons on 24 April 2007 of:


(i)  An increase in the notional allocation of Ordinary Share ADRs on 20 April
     2007 at a price of $59.35 per share:-

     Mrs C Bruck Slaoui    2


(ii) A decrease in the notional allocation of Ordinary Share ADRs on 20 April
     2007 at a price of $59.35 per share:-

     Dr R G Greig          1


This notification relates to a transaction notified in accordance with
Disclosure Rules 3.1.4R(1)(a) and 3.1.4R(1)(b).



S M Bicknell

Company Secretary



24 April 2007


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