Director/PDMR Shareholding

GlaxoSmithKline PLC
25 October 2007



   Notification of Transactions of Directors, Persons Discharging Managerial
                      Responsibility or Connected Persons


The Administrators of the GlaxoSmithKline Annual Investment Plan notified the
Company and the under mentioned persons on 25 October 2007 of an increase in
their interests in Ordinary shares at a price of £12.56 per share following the
re-investment of the dividend paid to shareholders on 11 October 2007:-

     Dr M M Slaoui                                          206
     Mr R M Bondy                                           265
     Mr M M Dunoyer                                         99
     Mr D Learmouth                                         17
     Dr D Pulman                                            152
     Mr A P Witty                                           92

This notification relates to transactions notified in accordance with Disclosure
and Transparency Rule 3.1.4R(1)(a).


S M Bicknell
Company Secretary

25 October 2007


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