Director/PDMR Shareholding

GlaxoSmithKline PLC
07 October 2005





   Notification of Transactions of Directors, Persons Discharging Managerial
                      Responsibility or Connected Persons





I give below details of changes in interests in the Ordinary Shares of
GlaxoSmithKline plc in respect of the under-mentioned person, arising from the
purchase of Ordinary Shares on 06 October 2005 under a Single Company ISA at a
price of £14.45 per Ordinary Share:


Mr J Heslop                                 4



The Company and the above named person were advised of this information on 07
October 2005.



This notification relates to a transaction notified in accordance with
Disclosure Rule 3.1.4R(1)(b).






S M Bicknell

Company Secretary



07 October 2005


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