Director/PDMR Shareholding

GlaxoSmithKline PLC
06 February 2007



   Notification of Transactions of Directors, Persons Discharging Managerial
                      Responsibility or Connected Persons



I give below details of changes in the interests of Directors, Persons
Discharging Managerial Responsibility or Connected Persons in the Ordinary
Shares of GlaxoSmithKline plc.




   29 January 2007         The Administrators of the SmithKline Beecham Employee Benefit Trust ("the
                           Trust") notified the Company on 6 February 2007 that 377 Ordinary shares in
                           the Company had been sold on 29 January 2007 on behalf of a participant in the
                           SmithKline Beecham Annual Investment Plan at a price of £13.90 per share.



                           The Trust also notified the Company on 6 February 2007 that 1,239 Ordinary
                           shares had been transferred from the Trust to a participant in the SmithKline
                           Beecham Annual Investment Plan.


The Trust is a discretionary fund of which all non US employees or former
employees of GlaxoSmithKline plc and its subsidiaries are potential
beneficiaries. One of the Company's directors, Mr J S Heslop is therefore
interested in the shares held in the fund from time to time in the same way as
other non US employees or former employees of GlaxoSmithKline plc and its
subsidiaries.



This notification relates to a transaction notified in accordance with
Disclosure Rule 3.1.4R(1)(b).





S M Bicknell
Company Secretary



6 February 2007






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