Director/PDMR Shareholding

GlaxoSmithKline PLC
09 October 2006



   Notification of Transactions of Directors, Persons Discharging Managerial
                      Responsibility or Connected Persons



I give below details of changes in the interests of Directors, Persons
Discharging Managerial Responsibility or Connected Persons in the Ordinary
Shares of GlaxoSmithKline plc in respect of the under-mentioned person(s)
arising from the purchase of Ordinary Shares at a price of £14.45 per Ordinary
Share on 5 October 2006 through the Company's ShareReward Plan ("the Plan")
which the under-mentioned persons entered on 5 October 2001:


Mr J S Heslop       Acquisition of 9 Ordinary Shares under the Dividend 
                    Reinvestment element of the Plan


Mr R Bondy          Acquisition of 9 Ordinary Shares under the Dividend 
                    Reinvestment element of the Plan


Mr D Learmouth      Acquisition of 9 Ordinary Shares under the Dividend 
                    Reinvestment element of the Plan


Dr D Pulman         Acquisition of 6 Ordinary Shares under the Dividend 
                    Reinvestment element of the Plan


Mr C Viehbacher     Acquisition of 2 Ordinary Shares under the Dividend 
                    Reinvestment element of the Plan


Mr A P Witty        Acquisition of 9 Ordinary Shares under the Dividend 
                    Reinvestment element of the Plan



The Company and the above-mentioned persons were advised of this information on
6 October 2006.


This notification relates to a transaction notified in accordance with
Disclosure Rules 3.1.4R(1)(a) and 3.1.4R(1)(b).




S M Bicknell
Company Secretary



9 October 2006






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