Director/PDMR Shareholding

GlaxoSmithKline PLC
30 November 2007


   Notification of Transactions of Directors, Persons Discharging Managerial
                      Responsibility or Connected Persons


I give below details of changes in interests in the Ordinary shares of
GlaxoSmithKline plc in respect of the under-mentioned Person Discharging
Managerial Responsibility:-

Mr J Clarke                   Sale of 7,746 Ordinary shares at a price of 
                              £12.80 per share on 30 November 2007


The Company was advised of this transaction on 30 November 2007.


This notification is in accordance with Disclosure and Transparency Rule 3.1.4R
(1)(a).


S M Bicknell
Company Secretary

30 November 2007


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