Director/PDMR Shareholding

GlaxoSmithKline PLC
20 October 2006






   Notification of Transactions of Directors, Persons Discharging Managerial
                      Responsibility or Connected Persons



I give below details of changes in the directors' interests in the American
Depository Shares (ADSs) of GlaxoSmithKline plc.



On 19 October 2006, the following Non-Executive Director was provisionally
allocated the following award over ADSs under the share allocation arrangements
for Non-Executive Directors for the period of service from 1 July 2006 to 30
September 2006 as listed below.  This additional allocation was in respect of Dr
Podolsky's position as the Board's nominated Scientific/Medical Expert.


Non Executive Director                        American Depository Shares (ADS)


Dr Daniel Podolsky                                         127.25





The Company and the director were informed of this allocation on 19 October
2006.



This notification relates to transactions notified in accordance with Disclosure
Rule 3.1.4R(1)(b).



S M Bicknell

Company Secretary



20 October 2006


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