Director/PDMR Shareholding

GlaxoSmithKline PLC
17 December 2007

   Notification of Transactions of Directors, Persons Discharging Managerial
                      Responsibility or Connected Persons



I give below details of changes in interests in the American Depositary Shares
(ADSs) of GlaxoSmithKline plc in respect of the under-mentioned Person
Discharging Managerial Responsibility:-




Mr D Stout        The sale on the 14 December 2007 of the following ADSs:




        Number of ADSs                        Sale Price

                                                (US$)
             3,761                              53.22
             9,148                              53.14



The Company was advised of the above transactions on the 14 December 2007.



This notification is in accordance with Disclosure and Transparency Rule 3.1.4R
(1)(a).



S M Bicknell
Company Secretary



17 December 2007


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