Director/PDMR Shareholding

GlaxoSmithKline PLC
15 June 2006



   Notification of Transactions of Directors, Persons Discharging Managerial
                      Responsibility or Connected Persons

I give below details of changes in the interests of Directors, Persons
Discharging Managerial Responsibility or Connected Persons in the Ordinary
Shares of GlaxoSmithKline plc in respect of the undermentioned persons arising
from the purchase of Ordinary Shares at a price of £14.90 per Ordinary Share on
09 June 2006 through the Company's ShareReward Plan ("the Plan") which the
undermentioned persons entered on 5 October 2001:


Mr J S Heslop      Acquisition of 8 Ordinary Shares under the partnership 
                   element of the Plan (personal contribution)

                   Acquisition of 8 Ordinary Shares under the matching element 
                   of the Plan (Company contribution)

Mr R Bondy         Acquisition of 8 Ordinary Shares under the partnership 
                   element of the Plan (personal contribution)

                   Acquisition of 8 Ordinary Shares under the matching element 
                   of the Plan (Company contribution)

Mrs J V Younger    Acquisition of 8 Ordinary Shares under the partnership 
                   element of the Plan (personal contribution)

                   Acquisition of 8 Ordinary Shares under the matching element 
                   of the Plan (Company contribution)

Mr A P Witty       Acquisition of 8 Ordinary Shares under the partnership 
                   element of the Plan (personal contribution)

                   Acquisition of 8 Ordinary Shares under the matching element 
                   of the Plan (Company contribution)


The above named individuals and the Company were advised of this information on
12 June 2006.

This notification relates to a transaction notified in accordance with
Disclosure Rules 3.1.4R(1)(a) and 3.1.4R(1)(b).



S M Bicknell
Company Secretary



15 June 2006




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