Director/PDMR Shareholding

GlaxoSmithKline PLC
13 February 2006


   Notification of Transactions of Directors, Persons Discharging Managerial
                      Responsibility or Connected Persons


I give below details of changes in the interests of Directors, Persons
Discharging Managerial Responsibility or Connected Persons in the Ordinary
Shares of GlaxoSmithKline plc in respect of the under-mentioned persons arising
from the purchase of Ordinary Shares at a price of £14.79 per Ordinary Share on
9 February 2006 through the Company's ShareReward Plan ("the Plan") which the
under-mentioned persons entered on 5 October 2001:


Mr J S Heslop     Acquisition of 9 Ordinary Shares under the partnership element 
                  of the Plan (personal contribution)

                  Acquisition of 9 Ordinary Shares under the matching element of 
                  the Plan (Company contribution)

Mr R Bondy        Acquisition of 9 Ordinary Shares under the partnership element 
                  of the Plan (personal contribution)

                  Acquisition of 9 Ordinary Shares under the matching element of 
                  the Plan (Company contribution)

Mrs J V Younger   Acquisition of 9 Ordinary Shares under the partnership element 
                  of the Plan (personal contribution)

                  Acquisition of 9 Ordinary Shares under the matching element of 
                  the Plan (Company contribution)

Mr A P Witty      Acquisition of 9 Ordinary Shares under the partnership element 
                  of the Plan (personal contribution)

                  Acquisition of 9 Ordinary Shares under the matching element of 
                  the Plan (Company contribution)


The Company and the above-mentioned persons were advised of this information on
10 February 2006.

This notification relates to a transaction notified in accordance with
Disclosure Rules 3.1.4 R (1) (a) and 3.1.4 R (1) (b).


S M Bicknell
Company Secretary

13 February 2006


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