Director/PDMR Shareholding

GlaxoSmithKline PLC
13 October 2005


   Notification of Transactions of Directors, Persons Discharging Managerial
                      Responsibility or Connected Persons


The Administrators of the GlaxoSmithKline Performance Share Plan notified the
Company and the under-mentioned persons on 13 October 2005 of an increase in
their interests in Ordinary Share ADRs at a price of $51.51 per ADR following
the re-investment of the dividend paid to shareholders on 06 October 2005.

Dr W Calhoun                                               35.127
Dr J P Garnier                                             245.956
Mr D Phelan                                                52.704


This notification relates to a transaction notified in accordance with
Disclosure Rules 3.1.4R(1)(a) and 3.1.4R(1)(b).


S M Bicknell
Company Secretary

13 October 2005




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