Director/PDMR Shareholding

GlaxoSmithKline PLC
17 October 2005


   Notification of Transactions of Directors, Persons Discharging Managerial
                      Responsibility or Connected Persons

I give below details of changes in interests in the Ordinary Share ADRs of
GlaxoSmithKline plc in respect of the under-mentioned person arising from the
reinvestment of the dividend paid to Ordinary Share ADR holders on 06 October
2005 through the US Global BuyDirect Plan administered by The Bank of New York:

Mrs P Phelan acquired a beneficial interest in 0.2079 Ordinary Share ADRs
purchased at a price of $51.7636 per ADR.


The Company and the above named person were advised of this information on 17
October 2005.

This notification relates to a transaction notified in accordance with
Disclosure Rule 3.1.4R(1)(a).


S M Bicknell
Company Secretary

17 October 2005


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