Director/PDMR Shareholding

GlaxoSmithKline PLC
14 February 2006



   Notification of Transactions of Directors, Persons Discharging Managerial
                      Responsibility or Connected Persons



I give below details of changes in the interests of Directors, Persons
Discharging Managerial Responsibility or Connected Persons in the Ordinary
Shares of GlaxoSmithKline plc.




7 February 2006  The Administrators of the SmithKline Beecham Employee Benefit 
                 Trust ("the Trust") notified the Company on 13 February 2006 
                 that 93 Ordinary shares had been transferred from the Trust to 
                 a participant in the GlaxoSmithKline Annual Investment Plan.



The Trust is a discretionary fund of which all non US employees or former
employees of GlaxoSmithKline plc and its subsidiaries are potential
beneficiaries. One of the Company's directors, Mr J Heslop is therefore
interested in the shares held in the fund from time to time in the same way as
other non US employees or former employees of GlaxoSmithKline plc and its
subsidiaries.



This notification relates to a transaction notified in accordance with
Disclosure Rule 3.1 4R (1) (b).



S M Bicknell

Company Secretary



14 February 2006




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