Director/PDMR Shareholding

GlaxoSmithKline PLC
26 February 2007





   Notification of Transactions of Directors, Persons Discharging Managerial
                      Responsibility or Connected Persons



I give below details of changes in the interests of Directors, Persons
Discharging Managerial Responsibility or Connected Persons in the Ordinary
Shares and Ordinary Share ADRs ("ADRs") of GlaxoSmithKline plc.


   21 February 2007              Abacus (GSK) Trustees Limited, as trustee of the
                                 GlaxoSmithKline Employee Trust, ("the GSK Trust"), transferred
                                 8,711 Ordinary Shares in the Company to participants in the
                                 SmithKline Beecham Employee Share Option Plan 1991.


   21 February 2007              The GSK Trust exchanged 10,735,474 Ordinary Shares in the
                                 Company for 5,367,737 ADRs in the Company. The GSK Trust sold
                                 5,367,737 ADRs in the Company at a price of $58.00 per ADR.


   21 February 2007              Abacus Corporate Trustees Limited, as trustee of the
                                 GlaxoSmithKline (US) Trust, ("the GSK US Trust"), purchased
                                 5,367,737 ADRs at a price of $58.00 per ADR.



The Company was advised of these transactions on 26 February 2007.



The GSK Trust is a discretionary trust of which all employees or former
employees of GlaxoSmithKline plc and its subsidiaries are potential
beneficiaries. Three of the Company's directors, Dr J-P Garnier, Dr M M Slaoui
and Mr J S Heslop are therefore interested in the shares held in the GSK Trust
from time to time in the same way as other employees or former employees of
GlaxoSmithKline plc and its subsidiaries.



The GSK US Trust is a grantor trust of which all employees or former employees
of SmithKline Beecham Corporation and its subsidiaries are potential
beneficiaries. Two of the Company's directors, Dr J-P Garnier and Dr M M Slaoui
are therefore interested in the shares held in the GSK US Trust from time to
time in the same way as other employees or former employees of SmithKline
Beecham Corporation and its subsidiaries.



This notification relates to a transaction notified in accordance with
Disclosure Rule 3.1.4R(1)(b).







S M Bicknell

Company Secretary



26 February 2007


                      This information is provided by RNS
            The company news service from the London Stock Exchange