Director/PDMR Shareholding

GlaxoSmithKline PLC
25 October 2005



   Notification of Transactions of Directors, Persons Discharging Managerial
                      Responsibility or Connected Persons


The Administrators of the GlaxoSmithKline Annual Investment Plan notified the
Company and the under mentioned persons on 25 October 2005 of an increase in
their interests in Ordinary Shares at a price of £14.54 per share following the
re-investment of the dividend paid to shareholders on 06 October 2005:-

Mr R Bondy                                        180

Mr M Dunoyer                                      67

Dr D Pulman                                       102

Mrs J Younger                                     156

Mr A Witty                                        62


This notification relates to a transaction notified in accordance with
Disclosure Rule 3.1.4R(1)(a).


S M Bicknell
Company Secretary


25 October 2005


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