Director/PDMR Shareholding

GlaxoSmithKline PLC
10 July 2006


   Notification of Transactions of Directors, Persons Discharging Managerial
                      Responsibility or Connected Persons


I give below details of changes in the interests of Directors, Persons
Discharging Managerial Responsibility or Connected Persons in the Ordinary
Shares of GlaxoSmithKline plc in respect of the under-mentioned persons arising
from the purchase of Ordinary Shares at a price of £15.26 per Ordinary Share on
6 July 2006 through the Company's ShareReward Plan ("the Plan") which the
under-mentioned persons entered on 5 October 2001:


Mr J S Heslop       Acquisition of 8 Ordinary Shares under the Dividend 
                    Reinvestment element of the Plan

Mr R Bondy          Acquisition of 8 Ordinary Shares under the Dividend 
                    Reinvestment element of the Plan

Mr D Learmouth      Acquisition of 8 Ordinary Shares under the Dividend 
                    Reinvestment element of the Plan

Dr D Pulman         Acquisition of 5 Ordinary Shares under the Dividend 
                    Reinvestment element of the Plan

Mr C Viehbacher     Acquisition of 2 Ordinary Shares under the Dividend 
                    Reinvestment element of the Plan

Mr A P Witty        Acquisition of 8 Ordinary Shares under the Dividend 
                    Reinvestment element of the Plan


The Company and the above-mentioned persons were advised of this information on
7 July 2006.

This notification relates to a transaction notified in accordance with
Disclosure Rules 3.1.4R(1)(a) and 3.1.4R(1)(b).


S M Bicknell
Company Secretary

10 July 2006


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