Director/PDMR Shareholding

GlaxoSmithKline PLC
05 March 2007






   Notification of Transactions of Directors, Persons Discharging Managerial
                      Responsibility or Connected Persons



Following a re-valuation of the cash element of the notional investment held
within the US Retirement Savings Plan ("The Plan"), which is notionally held in
GSK Ordinary Share ADRs, the Administrators of the Plan notified GlaxoSmithKline
plc and the under-mentioned persons on 2 March 2007 of:

(i)  An increase in the notional allocation of Ordinary Share ADRs on 23
February 2007 at a price of $56.92 per share:-

Dr JP Garnier                                                          35
Dr M M Slaoui                                                          7
Mrs C Bruck Slaoui                                                     3
Dr R G Greig                                                           21
Mr W Louv                                                              5
Dr D Pulman                                                            6
Mr D Stout                                                             42
Mr C Viehbacher                                                        8



(ii)  A decrease in the notional allocation of Ordinary Share ADRs on 9 February
2007 at a price of $56.38 per share:-

Dr M M Slaoui                         54



(iii)  A decrease in the notional allocation of Ordinary Share ADRs on 15
February 2007 at a price of $57.65 per share:-

Dr M M Slaoui                          1



This notification relates to a transaction notified in accordance with
Disclosure Rules 3.1.4R(1)(a) and 3.1.4R(1)(b).



S M Bicknell

Company Secretary



5 March 2007


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