Director/PDMR Shareholding

GlaxoSmithKline PLC
06 March 2007





   Notification of Transactions of Directors, Persons Discharging Managerial
                      Responsibility or Connected Persons



I give below details of changes in the interests of Directors, Persons
Discharging Managerial Responsibility or Connected Persons in the Ordinary
Shares of GlaxoSmithKline plc.




   27 February 2007        The Administrators of the SmithKline Beecham Employee Benefit Trust ("the
                           Trust") notified the Company on 5 March 2007 that 667 Ordinary shares in the
                           Company had been sold on 27 February 2007 on behalf of participants in the
                           SmithKline Beecham Annual Investment Plan at a price of £14.39 per share.



                           The Administrators of the Trust further notified the Company on 5 March 2007
                           that 1,013 Ordinary shares had been sold on 27 February 2007 on behalf of
                           participants in the SmithKline Beecham Bonus Investment Plan at a price of
                           £14.39 per share.







The Trust is a discretionary fund of which all non US employees or former
employees of GlaxoSmithKline plc and its subsidiaries are potential
beneficiaries. One of the Company's directors, Mr J S Heslop is therefore
interested in the shares held in the fund from time to time in the same way as
other non US employees or former employees of GlaxoSmithKline plc and its
subsidiaries.



This notification relates to a transaction notified in accordance with
Disclosure Rule 3.1.4R(1)(b).





S M Bicknell

Company Secretary



6 March 2007


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