Director/PDMR Shareholding

GlaxoSmithKline PLC
04 July 2005


   Notification of Transactions of Directors, Persons Discharging Managerial
                      Responsibility or Connected Persons

I give below details of changes in the interests of Directors, Persons
Discharging Managerial Responsibility or Connected Persons in the Ordinary
Shares of GlaxoSmithKline plc.


27 June 2005            The Administrators of the Trust notified the Company on 
                        4 July 2005 that 7,310 Ordinary shares in the Company 
                        had been sold on behalf of a participant in the
                        SmithKline Beecham Bonus Investment Plan at a price of 
                        £13.2925.

                        The Trust also notified the Company on 4 July 2005 that 
                        10,389 Ordinary shares had been transferred from the 
                        Trust to a participant in the SmithKline Beecham Bonus 
                        Investment Plan.


The Trust is a discretionary fund of which all non US employees or former
employees of GlaxoSmithKline plc and its subsidiaries are potential
beneficiaries. One of the Company's directors, Julian Heslop is therefore
interested in the shares held in the fund from time to time in the same way as
other non US employees or former employees of GlaxoSmithKline plc and its
subsidiaries.

This notification relates to a transaction notified in accordance with
Disclosure Rule 3.1.4R(1)(b).

S M Bicknell
Company Secretary

4 July 2005



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