Director/PDMR Shareholding

GlaxoSmithKline PLC
11 July 2005


   Notification of Transactions of Directors, Persons Discharging Managerial
                      Responsibility or Connected Persons

I give below details of changes in the interests of Directors, Persons
Discharging Managerial Responsibility or Connected Persons in the Ordinary
Shares of GlaxoSmithKline plc in respect of the under-mentioned persons arising
from the purchase of Ordinary Shares at a price of £13.51 per Ordinary Share on
7 July 2005 through the Company's ShareReward Plan ("the Plan") which the
under-mentioned persons entered on 5 October 2001:

Mr J Heslop                      Acquisition of 7 Ordinary Shares under the 
                                 Dividend Reinvestment element of the Plan

Mr R Bondy                       Acquisition of 7 Ordinary Shares under the 
                                 Dividend Reinvestment element of the Plan

Dr D Pulman                      Acquisition of 5 Ordinary Shares under the 
                                 Dividend Reinvestment element of the Plan

Mr C Viehbacher                  Acquisition of 2 Ordinary Shares under the 
                                 Dividend Reinvestment element of the Plan

Mr A Witty                       Acquisition of 7 Ordinary Shares under the 
                                 Dividend Reinvestment element of the Plan

Mrs J Younger                    Acquisition of 7 Ordinary Shares under the 
                                 Dividend Reinvestment element of the Plan


The Company and the above-mentioned persons were advised of this information on
8 July 2005.

This notification relates to a transaction notified in accordance with
Disclosure Rules 3.1.4R(1)(a) and 3.1.4R(1)(b).


S M Bicknell
Company Secretary

11 July 2005



                      This information is provided by RNS
            The company news service from the London Stock Exchange