Director/PDMR Shareholding

GlaxoSmithKline PLC
11 July 2005


         Notification of Transactions of Directors, Persons Discharging

                 Managerial Responsibility or Connected Persons

The Administrators of the GlaxoSmithKline Performance Share Plan notified the
Company and the under-mentioned persons on 11 July 2005 of an increase in their
notional interests in Ordinary Shares at a price of £13.39 per Ordinary Share
and Ordinary Share ADRs at a price of $49.95 per ADR following the notional
re-investment of the dividend paid to shareholders on 7 July 2005:

Dr J P Garnier                         3,131.377       ADRs

Mr J Heslop                              116.870       Ordinary Shares

Dr T Yamada                              939.413       ADRs

Mr R Bondy                             1,183.698       Ordinary Shares

Mr W Calhoun                             391.423       ADRs

Mr M Dunoyer                             445.808       Ordinary Shares

Mr R Greig                               391.423       ADRs

Mr D Phelan                               602.79       ADRs

Dr D Pulman                              391.634       Ordinary Shares
                                         192.018       ADRs

Mr D Stout                             1,158.609       ADRs

Mr C Viehbacher                           602.79       ADRs

Mr A Witty                             1,042.709       Ordinary Shares

Mrs J Younger                            269.022       Ordinary Shares

Mr J Ziegler                              602.79       ADRs

The notional dividends accrued will be paid out in proportion to the percentage
of participants' Performance Share Plan holdings that vest following the end of
the relevant three year measurement period.

This notification relates to a transaction notified in accordance with
Disclosure Rules 3.1.4R(1)(a) and 3.1.4R(1)(b).

S M Bicknell
Company Secretary

11 July 2005



                      This information is provided by RNS
            The company news service from the London Stock Exchange        VFLFFEDBFBBZ