Director/PDMR Shareholding

GlaxoSmithKline PLC
11 July 2005



   Notification of Transactions of Directors, Persons Discharging Managerial
                      Responsibility or Connected Persons

The Administrators of the GlaxoSmithKline Performance Share Plan notified the
Company and the under-mentioned persons on 11 July 2005 of an increase in their
interests in Ordinary Share ADRs at a price of $47.625 per ADR following the
re-investment of the dividend paid to shareholders on 7 July 2005.


Dr J P Garnier                                             288.432

Mr W Calhoun                                               41.193

Mr D Phelan                                                61.806


This notification relates to a transaction notified in accordance with
Disclosure Rules 3.1.4R(1)(a) and 3.1.4R(1)(b).

S M Bicknell
Company Secretary

11 July 2005


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