Director/PDMR Shareholding

GlaxoSmithKline PLC
11 July 2005


   Notification of Transactions of Directors, Persons Discharging Managerial
                      Responsibility or Connected Persons

The Administrators of the SmithKline Beecham Mid-Term Incentive Plan notified
the Company and the under-mentioned persons on 11 July 2005 of an increase in
their interests in Ordinary Share ADRs at a price of $47.625 per ADR following
the re-investment of the dividend paid to shareholders on 7 July 2005.

Dr J P Garnier                                             1,324.903

Mr W Calhoun                                               135.419

Mr D Phelan                                                255.534

Mr D Stout                                                 102.138

Mr J Ziegler                                               82.445


This notification relates to a transaction notified in accordance with
Disclosure Rules 3.1.4R(1)(a) and 3.1.4R(1)(b).

S M Bicknell
Company Secretary

11 July 2005


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