Director/PDMR Shareholding

GlaxoSmithKline PLC
13 March 2007




   Notification of Transactions of Directors, Persons Discharging Managerial
                      Responsibility or Connected Persons



I give below details of changes in the interests of Directors, Persons
Discharging Managerial Responsibility or Connected Persons in the Ordinary
Shares and Ordinary Share ADRs ("ADRs") of GlaxoSmithKline plc.


   12 March 2007       Abacus (GSK) Trustees Limited, as trustee of the
                       GlaxoSmithKline Employee Trust ("the GSK Trust"), 
                       transferred 19,933 Ordinary Shares in the Company to 
                       participants in the SmithKline Beecham Employee Share 
                       Option Plan 1991.

                       The GSK Trust sold 11,326 American Depositary Receipts 
                       (ADRs) in the Company on behalf of participants in the 
                       SmithKline Beecham Mid-Term Incentive Plan at a price 
                       of $55.49 per ADR.

                       The GSK Trust transferred 19,988 ADRs in the Company to
                       participants in the SmithKline Beecham Mid-Term Incentive 
                       Plan.


The Company was advised of these transactions on 13 March 2007.

The GSK Trust is a discretionary trust of which all employees or former
employees of GlaxoSmithKline plc and its subsidiaries are potential
beneficiaries. Three of the Company's directors, Dr J-P Garnier, Dr M M Slaoui
and Mr J S Heslop are therefore interested in the shares held in the GSK Trust
from time to time in the same way as other employees or former employees of
GlaxoSmithKline plc and its subsidiaries.

This notification relates to a transaction notified in accordance with
Disclosure Rule 3.1.4R(1)(b).




S M Bicknell
Company Secretary


13 March 2007



                      This information is provided by RNS
            The company news service from the London Stock Exchange