Director/PDMR Shareholding

GlaxoSmithKline PLC
21 July 2005


   Notification of Transactions of Directors, Persons Discharging Managerial
                      Responsibility or Connected Persons


Following a re-valuation of the cash element of the notional investment held
within the US Retirement Savings Plan, which is notionally held in GSK Ordinary
Share ADRs, the Administrators of the Plan notified GlaxoSmithKline plc and the
under-mentioned person on 21 July 2005 of an increase in the notional allocation
of Ordinary Share ADRs on 15 July 2005 at a price of $47.99 per share:-

     Russell Greig                                        3


This notification relates to a transaction notified in accordance with
Disclosure rule

 3.1.4R(1)(a).


S M Bicknell
Company Secretary
21 July 2005


                      This information is provided by RNS
            The company news service from the London Stock Exchange