Director/PDMR Shareholding

GlaxoSmithKline PLC
07 August 2006



   Notification of Transactions of Directors, Persons Discharging Managerial
                      Responsibility or Connected Persons



Following a re-valuation of the cash element of the notional investment held
within the US Retirement Savings Plan ("The Plan"), which is notionally held in
GSK Ordinary Share ADRs, the Administrators of the Plan notified GlaxoSmithKline
plc and the under-mentioned persons on 4 August 2006 of an increase in the
notional allocation of Ordinary Share ADRs on 3 August 2006 at a price of $53.89
per share:-


Dr F Calhoun                                                           10
Dr JP Garnier                                                          50
Mr D Phelan                                                            152
Dr D Pulman                                                            11
Mr D Stout                                                             25
Mr C Viehbacher                                                        3
Dr R Greig                                                             61



This notification relates to a transaction notified in accordance with
Disclosure Rules 3.1.4R(1)(a) and 3.1.4R(1)(b).



S M Bicknell

Company Secretary

7 August 2006


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