Director/PDMR Shareholding

GlaxoSmithKline PLC
30 March 2006



   Notification of Transactions of Directors, Persons Discharging Managerial
                      Responsibility or Connected Persons



I give below details of changes in the interests of Directors, Persons
Discharging Managerial Responsibility or Connected Persons in the Ordinary
Shares of GlaxoSmithKline plc.


   24 March 2006                 Abacus (GSK) Trustees Limited, as trustee of the
                                 GlaxoSmithKline Employee Trust, ("the GSK Trust"), transferred
                                 28,565 Ordinary Shares in the Company to participants in the
                                 SmithKline Beecham Employee Share Option Plan 1991.


   27 March 2006                 The GSK Trust, as trustee of the GlaxoSmithKline Employee
                                 Trust, transferred 19,036 Ordinary Shares in the Company to
                                 participants in the SmithKline Beecham Employee Share Option
                                 Plan 1991.


   28 March 2006                 The GSK Trust, as trustee of the GlaxoSmithKline Employee
                                 Trust, transferred 34,420 Ordinary Shares in the Company to
                                 participants in the SmithKline Beecham Employee Share Option
                                 Plan 1991.



The Company was advised of these transactions on 30, 29 and 30 March 2006
respectively.



We have also been advised by the GSK Trust that the transfer on the 1 March 2006
of 14,143 Ordinary shares was incorrectly notified in that the number actually
transferred was 12,043 and not as previously advised 14,143.



The GSK Trust is a discretionary trust of which all employees or former
employees of GlaxoSmithKline plc and its subsidiaries are potential
beneficiaries. Three of the Company's directors, Dr J-P Garnier, Dr T Yamada and
Mr J S Heslop are therefore interested in the shares held in the GSK Trust from
time to time in the same way as other employees or former employees of
GlaxoSmithKline plc and its subsidiaries.



This notification relates to a transaction notified in accordance with
Disclosure Rule 3.1.4 R (1) (b).







S M Bicknell

Company Secretary



30 March 2006


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