Director/PDMR Shareholding

GlaxoSmithKline PLC
22 August 2005


   Notification of Transactions of Directors, Persons Discharging Managerial
                      Responsibility or Connected Persons

I give below details of a decrease in interests in the Ordinary Shares ADRs of
GlaxoSmithKline plc in respect of the personal holdings of the under-mentioned
person at a price of $47.97 per ADR, following the sale of ADRs on 15 August
2005.


Mr R Greig                                                 879


The Company and Mr Greig were advised of this information on 22 August 2005.

This notification relates to a transaction notified in accordance with
Disclosure Rule 3.1.4R(1)(a).

S M Bicknell
Company Secretary

22 August 2005


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