Director/PDMR Shareholding

GlaxoSmithKline PLC
22 August 2005


   Notification of Transactions of Directors, Persons Discharging Managerial
                      Responsibility or Connected Persons

The Administrators of the GlaxoSmithKline Annual Investment Plan notified the
Company and the under mentioned person on 19 August 2005 of an increase in their
interests in Ordinary Shares following the distribution of shares on 11 August
resulting from the maturity of the 2002 election under the GlaxoSmithKline
Annual Investment Plan:-

Mrs J Younger                                     3,486

This notification relates to a transaction notified in accordance with
Disclosure Rule 3.1.4R(1)(a).

S M Bicknell
Company Secretary

22 August 2005




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