Director Shareholding

GlaxoSmithKline PLC
9 January 2001

                             Directors' Interests



I give below details of changes in directors' interests in the Ordinary Shares
of GlaxoSmithKline plc:

The following non-executive directors of the Company were provisionally
allocated the following ordinary shares under the SmithKline Beecham plc share
election arrangements for non-executive directors:

Non-Executive Directors Deferred Retainer Fees
Non-Executive Director  No. of Shares  Average Price (£)    Allocation Date
Sir Peter Walters       329.699        18.957               2nd January 2001
Dr L Shapiro            117.776        18.957               2nd January 2001
Mr J Young              124.913        18.957               2nd January 2001

Non-Executive Directors Share Allocation (Ordinary Shares) - Annual Dividend
Reinvestment
Non-Executive Director  No. of Shares   Average Price (£) Allocation Date
Sir Peter Walters       87.612          18.957            31st December 2000
Sir Christopher Hogg    6.33            18.957            31st December 2000
Baroness Hooper         6.33            18.957            31st December 2000
Sir Ian Prosser         6.33            18.957            31st December 2000
Dr L Shapiro            17.038          18.957            31st December 2000
Mr J Young              60.071          18.957            31st December 2000

Non-Executive Directors Share Allocation (ADR's) - Annual Dividend
Reinvestment
Non-Executive Director No. of ADRs Average Price ($)     Allocation Date
Mr P Allaire           3.31        56.0625               31st December 2000
Mr D McHenry           3.31        56.0625               31st December 2000
Dr L Shapiro           3.31        56.0625               31st December 2000
Mr J Young             3.31        56.0625               31st December 2000

The Company was notified of this information on 3rd January 2001.

S M Bicknell

Company Secretary


9th January 2001