Director Shareholding

GlaxoSmithKline PLC
30 July 2001



                             Directors' Interests



I give below details of changes in directors' interests in the Ordinary Shares
of GlaxoSmithKline plc.

27     Abacus (GW) Trustees Limited, as trustee of The Glaxo Wellcome Employee
July   Trust ('the Trust'), transferred 6,276 Ordinary Shares in the Company to
2001   participants of the Glaxo Wellcome UK Share Option Scheme, Glaxo Wellcome
       International Share Option Scheme and the Glaxo Wellcome Long Term
       Incentive Plan. The Trust also sold 1,546 Ordinary Shares in the Company
       at £20.03 per share.





The Company was advised of these transactions on 30 July 2001.




The Trust is a discretionary trust of which all employees or former employees
of Glaxo Wellcome plc and its subsidiaries are potential beneficiaries. Two of
the Company's directors, Sir Richard Sykes and John Coombe are therefore
interested in the shares held in the Trust from time to time in the same way
as other employees or former employees of Glaxo Wellcome plc and its
subsidiaries.






S M Bicknell

Company Secretary




30 July 2001