Director Shareholding

GlaxoSmithKline PLC 30 March 2001 Directors' Interests I give below details of changes in the directors' interests in the Ordinary Shares and American Depositary Shares (ADSs) of GlaxoSmithKline plc. On 29 March 2001, under the Rules of the GlaxoSmithKline Performance Share Plan, Target Awards were granted over Ordinary Shares and ADSs in the Company to the directors listed below: Ordinary Shares American Depository Shares Dr JP Garnier 70,000 Mr J D Coombe 40,000 On the same day, options to acquire the Company's Shares and ADSs were granted under the GlaxoSmithKline Share Option Plan to the directors listed below: Ordinary Subscription Price American Depository Subscription Shares Shares Price Dr JP 450,000 $51.30 Garnier Mr J D 290,000 £17.93 Coombe Under the terms of the GlaxoSmithKline Performance Share Plan (which was approved by Shareholders on 31 July 2000), Target Awards are granted annually to eligible executives, designating a number of Shares/ADSs that may be awarded, dependent upon the Company's performance over a three year measurement period. The three year measurement period for the Target Awards granted on 29 March 2001 commenced on 1 January 2001 and ends on 31 December 2003. The grant of options is made under the GlaxoSmithKline Share Option Plan which was approved by Shareholders on 31st July 2000. A performance condition has been set for the vesting of the options granted to the above directors. S M Bicknell Company Secretary 30 March 2001

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