Director Shareholding

GlaxoSmithKline PLC
2 July 2001



                             Directors' Interests


I give below details of changes in directors' interests in the Ordinary Shares
of GlaxoSmithKline plc.

28   Abacus (GW) Trustees Limited, as trustee of The Glaxo Wellcome Employee
June Trust ('the Trust'), transferred 240,265 Ordinary Shares in the Company to
2001 participants of the Glaxo Wellcome 1999 Share Option Plan, the Glaxo
     Wellcome International Share Option Scheme and the Glaxo Wellcome UK Share
     Option Scheme. The Trust also sold 21,905 Ordinary Shares in the Company
     at £20.00 per share.


The Company was advised of these transactions on 29 June 2001.


The Trust is a discretionary trust of which all employees or former employees
of Glaxo Wellcome plc and its subsidiaries are potential beneficiaries. Two of
the Company's directors, Sir Richard Sykes and John Coombe are therefore
interested in the shares held in the Trust from time to time in the same way
as other employees or former employees of Glaxo Wellcome plc and its
subsidiaries.


S M Bicknell

Company Secretary


2 July 2001