Director Shareholding

GlaxoSmithKline PLC
9 July 2001

                             Directors' Interests



I give below details of changes in directors' interests in the Ordinary Shares
of GlaxoSmithKline plc.

5    Abacus (GW) Trustees Limited, as trustee of The Glaxo Wellcome Employee
July Trust ('the Trust'), transferred 145,185 Ordinary Shares in the Company to
2001 participants of the Glaxo Wellcome 1999 Share Option Plan, the Glaxo
     Wellcome UK Share Option Scheme and the Glaxo Wellcome International Share
     Option Scheme.





The Company was advised of this transaction on 6 July 2001.




The Trust is a discretionary trust of which all employees or former employees
of Glaxo Wellcome plc and its subsidiaries are potential beneficiaries. Two of
the Company's directors, Sir Richard Sykes and John Coombe are therefore
interested in the shares held in the Trust from time to time in the same way
as other employees or former employees of Glaxo Wellcome plc and its
subsidiaries.




S M Bicknell

Company Secretary




9 July 2001