Director Shareholding

GlaxoSmithKline PLC
26 July 2001



                             Directors' Interests

I give below details of changes in directors' interests in the Ordinary Shares
of GlaxoSmithKline plc.

24    Abacus (GW) Trustees Limited, as trustee of The Glaxo Wellcome Employee
July  Trust ('the Trust'), transferred 34,345 Ordinary Shares in the Company to
2001  participants of the Glaxo Wellcome 1999 Share Option Plan, Glaxo Wellcome
      UK Share Option Scheme and the Glaxo Wellcome International Share Option
      Scheme.

The Company was advised of this transaction on 25 July 2001.

The Trust is a discretionary trust of which all employees or former employees
of Glaxo Wellcome plc and its subsidiaries are potential beneficiaries. Two of
the Company's directors, Sir Richard Sykes and John Coombe are therefore
interested in the shares held in the Trust from time to time in the same way
as other employees or former employees of Glaxo Wellcome plc and its
subsidiaries.



S M Bicknell

Company Secretary



26 July 2001