Director Shareholding

GlaxoSmithKline PLC 22 October 2001 Directors' Interests I give below details of changes in directors' interests in the Ordinary Shares of GlaxoSmithKline plc. 19 Abacus (GW) Trustees Limited, as trustee of The Glaxo Wellcome Employee October Trust ('the Trust'), transferred 37,191 Ordinary Shares in the Company 2001 to participants of the Glaxo Wellcome UK Share Option Scheme, the Glaxo Wellcome 1999 Share Option Plan and the Glaxo Wellcome International Share Option Scheme. The Company was advised of this transaction on 22 October 2001. The Trust is a discretionary trust of which all employees or former employees of GlaxoSmithKline Services plc (formerly Glaxo Wellcome plc) and its subsidiaries are potential beneficiaries. Two of the Company's directors, Sir Richard Sykes and John Coombe are therefore interested in the shares held in the Trust from time to time in the same way as other employees or former employees of GlaxoSmithKline Services plc and its subsidiaries. S M Bicknell Company Secretary 22 October 2001

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