Director Shareholding

GlaxoSmithKline PLC
6 November 2001

                             Director's Interests 


I give below details of changes in interests in the Ordinary Shares of
GlaxoSmithKline plc in respect of the under-mentioned director:-



Mr John D Coombe   Sold 10,000 Ordinary Shares in the Company on 6 November 
                   2001 at a price of £19.055 per share


  
The Company was advised of this transaction on 6 November 2001.




SM Bicknell

Company Secretary

6 November 2001