Director Shareholding

GlaxoSmithKline PLC
15 January 2002

                             Directors' Interests



I give below details of changes in directors' interests in the Ordinary Shares
of GlaxoSmithKline plc.

14       Abacus (GW) Trustees Limited, as trustee of The Glaxo Wellcome Employee
January  Trust ('the Trust'), transferred 2,809 Ordinary Shares in the Company
2002     to participants of the Glaxo Wellcome International Share Option
         Scheme.




The Company was advised of this transaction on 15 January 2002.




The Trust is a discretionary trust of which all employees or former employees
of GlaxoSmithKline Services plc (formerly Glaxo Wellcome plc) and its
subsidiaries are potential beneficiaries. Two of the Company's directors, Sir
Richard Sykes and John Coombe are therefore interested in the shares held in
the Trust from time to time in the same way as other employees or former
employees of GlaxoSmithKline Services plc and its subsidiaries.






S M Bicknell

Company Secretary




15 January 2002