Director Shareholding

GlaxoSmithKline PLC
15 February 2002



                              Directors' Interests

I give below details of changes in directors' interests in the Ordinary Shares
of GlaxoSmithKline plc.

14 February 2002                  The Administrators of the GlaxoSmithKline US 
                                  Retirement Savings Plan ('the Plan') notified 
                                  GlaxoSmithKline plc on the 15 February 2002, 
                                  that as a result of movement in the fund on 
                                  the 14 February 2002, the number of Ordinary 
                                  Share ADRs held by the fund had decreased from
                                  18,579,139 to 18,447,407 at an average price
                                  of $50.0500.

The Plan is a discretionary fund of which all employees or former employees of
SmithKline Beecham plc and its subsidiaries are potential beneficiaries. One of
the Company's directors, Dr J P Garnier is therefore, interested in the shares
held in the fund from time to time in the same way as other employees or former
employees of SmithKline Beecham plc and its subsidiaries.

S M Bicknell

Company Secretary

15 February 2002



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