Director Shareholding

GlaxoSmithKline PLC
18 February 2002

                              Directors' Interests



I give below details of changes in directors' interests in the Ordinary Shares
of GlaxoSmithKline plc.

15 February 2002    Abacus (GW) Trustees Limited, as trustee of The Glaxo 
                    Wellcome Employee Trust ('the Trust'), transferred 3,759 
                    Ordinary Shares in the Company to participants of
                    the Glaxo Wellcome International Share Option Scheme and the 
                    Glaxo Wellcome UK Share Option Scheme.




The Company was advised of this transaction on 18 February 2002.




The Trust is a discretionary trust of which all employees or former employees of
GlaxoSmithKline Services plc (formerly Glaxo Wellcome plc) and its subsidiaries
are potential beneficiaries. Two of the Company's directors, Sir Richard Sykes
and John Coombe are therefore interested in the shares held in the Trust from
time to time in the same way as other employees or former employees of
GlaxoSmithKline Services plc and its subsidiaries.



S M Bicknell
Company Secretary



18 February 2002




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