Director Shareholding

GlaxoSmithKline PLC
22 February 2002



                              Directors' Interests

I give below details of changes in directors' interests in the Ordinary Shares
of GlaxoSmithKline plc.

21 February 2002              Abacus (GW) Trustees Limited, as trustee of The 
                              Glaxo Wellcome Employee Trust ("the Trust"), 
                              transferred 6,554 Ordinary Shares in the Company 
                              to participants of the Glaxo Wellcome 
                              International Share Option Scheme.

The Company was advised of this transaction on 22 February 2002.

The Trust is a discretionary trust of which all employees or former employees of
GlaxoSmithKline Services plc (formerly Glaxo Wellcome plc) and its subsidiaries
are potential beneficiaries. Two of the Company's directors, Sir Richard Sykes
and John Coombe are therefore interested in the shares held in the Trust from
time to time in the same way as other employees or former employees of
GlaxoSmithKline Services plc and its subsidiaries.

S M Bicknell

Company Secretary


22 February 2002




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